3-(3-Bromophenyl)cyclobutanone
≥95%
Reagent
Code: #150621
CAS Number
885267-15-2
blur_circular Chemical Specifications
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Molecular Information
Weight
225.08 g/mol
Formula
C₁₀H₉BrO
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Registry Numbers
MDL Number
MFCD08706340
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Physical Properties
Boiling Point
307.4 °C at 760 mmHg
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Storage & Handling
Storage
2-8°C, dry, sealed
description Product Description
Used in organic synthesis as an intermediate for pharmaceuticals and bioactive compounds. Its cyclic ketone structure with an aryl bromide moiety makes it valuable in cross-coupling reactions, such as Suzuki or Heck reactions, to build complex aromatic and heterocyclic systems. Commonly employed in the development of central nervous system agents and anti-inflammatory drugs due to its ability to mimic phenylcyclohexyl scaffolds. Also utilized in medicinal chemistry for structure-activity relationship (SAR) studies, where the bromine allows for further functionalization and the cyclobutanone provides conformational rigidity.
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