3,3-Difluorocyclobutanecarboxylic Acid
98%
Reagent
Code: #174245
CAS Number
107496-54-8
blur_circular Chemical Specifications
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Molecular Information
Weight
136.10 g/mol
Formula
C₅H₆F₂O₂
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Registry Numbers
MDL Number
MFCD08705857
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Physical Properties
Melting Point
53°C
Boiling Point
205°C
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Storage & Handling
Storage
Room temperature, dry
description Product Description
Used as a key building block in pharmaceutical synthesis, particularly in the development of biologically active compounds. Its rigid cyclobutane structure and fluorine substitutions enhance metabolic stability and binding affinity in drug candidates. Commonly employed in the preparation of protease inhibitors and other therapeutic agents where fluorination improves pharmacokinetic properties. Also utilized in agrochemicals for creating structurally constrained intermediates that increase selectivity and efficacy. The carboxylic acid group allows for easy derivatization, enabling peptide coupling and ester formation in multi-step syntheses.
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