Hexaketocyclohexane hydrate is primarily utilized in organic synthesis as a precursor for the production of various complex organic compounds. Its structure makes it a valuable intermediate in the synthesis of polyphenolic compounds, which are important in the development of pharmaceuticals and agrochemicals. Additionally, it is employed in the preparation of advanced materials, particularly in the field of coordination chemistry, where it can act as a ligand to form metal-organic frameworks (MOFs) with potential applications in gas storage and catalysis. Its role in analytical chemistry is also notable, where it serves as a reagent for specific chemical reactions and assays.