Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of cubane-based drug candidates. Its rigid three-dimensional structure enhances metabolic stability and improves binding selectivity in bioactive molecules. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies, especially in designing protease inhibitors and central nervous system (CNS) agents. Also utilized in the preparation of peptidomimetics due to the amino acid-like functionality combined with the cubane scaffold’s unique geometry.