Used primarily in advanced organic synthesis, this compound serves as a high-energy scaffold in pharmaceutical research due to the strained cubane core. The iodine and carboxylic acid functional groups allow for further derivatization, making it valuable in the development of novel drug candidates, particularly in exploring metabolic stability and bioavailability. Its unique three-dimensional structure is exploited in medicinal chemistry to improve binding selectivity and resistance to enzymatic degradation. Additionally, it has been investigated in materials science for designing energetic or thermally stable compounds.