N,N'-Ethylenebis(maleamic acid) is primarily used in the field of polymer chemistry as a crosslinking agent. Its ability to form strong covalent bonds makes it valuable in the production of durable and stable polymers. This compound is often incorporated into resins and coatings to enhance their mechanical properties, such as hardness and resistance to heat and chemicals. Additionally, it is utilized in the synthesis of specialty adhesives, where it improves bonding strength and durability. In the biomedical field, it can be employed to create biocompatible materials for drug delivery systems or medical devices, owing to its reactive functional groups that allow for tailored modifications.