Used as a crosslinking agent in biomedical applications, particularly in the synthesis of hydrogels for drug delivery and tissue engineering. Its multiple carboxylic and amino groups allow for conjugation with biomolecules and polymers, enabling the formation of stable, biocompatible networks. Commonly employed in controlled release systems due to its ability to form pH-responsive matrices. Also utilized in modifying surfaces of medical devices to improve biointegration and reduce fouling.