N,N'-Bis(2-hydroxyethyl)oxamide finds application primarily as a crosslinking agent in the production of polymers and resins. It is used to enhance the mechanical properties, thermal stability, and durability of materials, making it valuable in coatings, adhesives, and elastomers. Additionally, it serves as a modifier in polyurethane foams, improving their flexibility and resilience. In the textile industry, it is utilized to impart wrinkle resistance and strength to fabrics. Its ability to act as a stabilizer and crosslinker also makes it suitable for use in personal care products, such as hair gels and creams, to improve texture and performance.