1,3,5-Tris(bromoethynyl)benzene is primarily utilized in the field of organic synthesis and materials science. It serves as a key building block for the creation of complex organic molecules, particularly in the development of advanced polymers and dendritic structures. Its bromoethynyl groups make it highly reactive, enabling efficient cross-coupling reactions, which are essential for constructing conjugated systems used in organic electronics.

In materials science, this compound is employed in the fabrication of light-emitting diodes (LEDs) and organic photovoltaic (OPV) devices due to its ability to form stable, highly conjugated frameworks. Its structural rigidity and electronic properties also make it a candidate for designing molecular wires and other nanoscale components in nanotechnology applications. Additionally, it is explored in the synthesis of flame retardants, leveraging its bromine content to enhance fire resistance in polymeric materials.