(2-Iodo-5-methoxyphenyl)boronic acid is primarily used in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions. This reaction is widely employed in the pharmaceutical industry to create complex organic compounds, including drug intermediates and active pharmaceutical ingredients (APIs). The compound's boronic acid group acts as a key functional group, enabling the formation of carbon-carbon bonds between aryl or vinyl groups, which is essential for constructing diverse molecular frameworks.

Additionally, it finds applications in material science, where it is used to synthesize advanced organic materials, such as polymers and liquid crystals, which are critical for electronic devices and display technologies. Its unique structure, combining iodine and methoxy groups, also makes it a valuable building block in the development of fluorescent probes and sensors for biochemical research. These probes are utilized in studying biological processes and detecting specific molecules in complex environments.

In medicinal chemistry, (2-Iodo-5-methoxyphenyl)boronic acid is explored for its potential in designing boron-containing drugs, leveraging boron's ability to interact with biological targets. This has implications in developing treatments for diseases such as cancer and bacterial infections. Overall, its versatility in chemical reactions and functional group compatibility makes it a valuable reagent in both industrial and academic research settings.