4-N-Boc-Amino-3-fluorophenylboronic acid
98%
Reagent
Code: #219791
CAS Number
218301-87-2
blur_circular Chemical Specifications
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Molecular Information
Weight
255.06 g/mol
Formula
C₁₁H₁₅BFNO₄
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Registry Numbers
MDL Number
MFCD03426360
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Storage & Handling
Storage
-20°C, Inert Gas
description Product Description
Used in Suzuki-Miyaura cross-coupling reactions for the synthesis of fluorinated biaryl compounds, particularly in pharmaceutical and agrochemical research. The Boc-protected amine and boronic acid functionalities allow for selective coupling and subsequent deprotection to build complex fluorinated aromatic structures. Commonly employed in the development of kinase inhibitors and other bioactive molecules where fluorine substitution enhances metabolic stability and binding affinity. Its protected amine group enables further derivatization after coupling, making it a valuable building block in medicinal chemistry.
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