Used extensively in peptide synthesis as a coupling reagent, it facilitates the formation of peptide bonds between amino acids. Its high reactivity and efficiency make it a preferred choice in solid-phase peptide synthesis, particularly for challenging sequences. Additionally, it is employed in the preparation of azides, which are valuable intermediates in organic synthesis, including click chemistry reactions such as azide-alkyne cycloaddition for creating complex heterocyclic structures. The compound's stability and solubility in organic solvents further enhance its utility in various chemical transformations, including drug development and biomaterials, making it a versatile tool in both academic research and industrial applications.