This chemical is primarily used as a peptide coupling reagent in organic synthesis, particularly in the formation of amide bonds. It is highly effective in facilitating the condensation of amino acids during solid-phase peptide synthesis (SPPS), offering high yields and minimal racemization. Its stability and reactivity make it suitable for complex peptide sequences, including those with sterically hindered amino acids. Additionally, it is employed in the synthesis of pharmaceuticals, agrochemicals, and other biologically active compounds where precise amide bond formation is critical. Its hexafluorophosphate counterion enhances solubility in organic solvents, making it versatile for various synthetic applications.