Widely used in organic synthesis as a coupling reagent, particularly in peptide bond formation and the activation of carboxylic acids. It promotes efficient amide coupling under mild conditions, making it valuable in pharmaceutical and medicinal chemistry. Also employed in the preparation of active esters and in dehydration reactions. Its stability and solubility in common organic solvents enhance its utility in multi-step synthetic routes. Frequently chosen for synthesizing complex molecules where high chemoselectivity is required.