Chromeazurol S is widely used as a metallochromic indicator in analytical chemistry, particularly for the detection and quantification of metal ions such as aluminum, iron, and beryllium. It forms colored complexes with these metals, enabling their visual or spectrophotometric determination in various samples. In environmental analysis, it helps monitor metal contamination in water and soil. Additionally, it is employed in biochemical research to study metal-binding proteins and enzymes, providing insights into their structure and function. Its sensitivity and specificity make it a valuable tool in both laboratory and industrial settings for metal ion analysis.