1,3,5-Tris(4-formylphenyl)benzene is widely used in the synthesis of advanced organic frameworks, particularly in the development of covalent organic frameworks (COFs). Its three aldehyde groups make it a valuable building block for creating highly porous and stable materials, which are essential for applications in gas storage, separation, and catalysis. Additionally, it serves as a key precursor in the design of fluorescent sensors and optoelectronic devices due to its ability to form conjugated structures with unique photophysical properties. Its role in constructing complex molecular architectures also extends to the field of supramolecular chemistry, where it aids in the formation of well-defined nanostructures for various functional applications.