2-Bromoamphetamine hydrochloride is primarily used in research settings, particularly in neuroscience and pharmacology studies. It serves as a tool compound to investigate the mechanisms of action of amphetamine derivatives and their effects on neurotransmitter systems, especially dopamine and serotonin. Researchers utilize it to explore the behavioral and physiological responses associated with stimulant drugs, aiding in the understanding of addiction and related disorders. Its structural similarity to other amphetamines makes it valuable for comparative studies, helping to elucidate the role of specific functional groups in drug activity. Additionally, it has been employed in the development of radiolabeled tracers for imaging studies to visualize and monitor neurotransmitter dynamics in the brain.