CGP 52608 is primarily utilized in research settings to study circadian rhythms and their regulation. It acts as a ligand for the retinoic acid receptor-related orphan receptor alpha (RORα), which plays a crucial role in the control of biological clocks. By modulating RORα activity, this compound helps researchers understand the molecular mechanisms behind circadian clock function and its impact on various physiological processes, such as sleep-wake cycles, metabolism, and immune responses. Additionally, CGP 52608 is used in experimental studies to explore potential therapeutic applications for circadian rhythm disorders, including sleep disorders and metabolic syndromes. Its ability to influence RORα makes it a valuable tool in the development of drugs targeting circadian-related diseases.