Used extensively in chromatography for the separation and purification of compounds. It is particularly effective in column chromatography, where it serves as the stationary phase to isolate components from complex mixtures based on their polarity and molecular size. Its high surface area and porosity make it ideal for adsorbing and separating a wide range of substances, including organic compounds, natural products, and pharmaceuticals. Additionally, it is employed in preparative chromatography for isolating larger quantities of materials for further analysis or use. Its versatility also extends to thin-layer chromatography (TLC) for analytical purposes, aiding in the identification and quantification of compounds in research and quality control processes.