Fenbendazole sulfone, also known as HOE 5151, is primarily used in veterinary medicine as an anthelmintic agent. It is effective against a wide range of parasitic worms, including gastrointestinal nematodes, lungworms, and certain types of tapeworms in animals such as cattle, sheep, goats, pigs, and horses. The compound works by disrupting the energy metabolism of the parasites, leading to their immobilization and eventual death.

In addition to its veterinary applications, Fenbendazole sulfone has been explored for potential use in human medicine, particularly in the treatment of certain parasitic infections and as a candidate for cancer therapy due to its ability to inhibit microtubule formation, which can disrupt cell division in rapidly proliferating cells. Research is ongoing to further understand its efficacy and safety in these contexts.

The compound is typically administered orally, often mixed with feed or water, making it convenient for large-scale treatment in livestock. Its broad-spectrum activity and relatively low toxicity to the host animals make it a valuable tool in maintaining animal health and productivity.