N,O-Bis(trimethylsilyl)acetamide (TMS-BA)

95%

Reagent Code: #93725
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Alias N,O-bis(trimethylsilyl)acetamide ; N,O-bistrimethylsilylacetamide
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CAS Number 10416-59-8

science Other reagents with same CAS 10416-59-8

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 203.43 g/mol
Formula C₈H₂₁NOSi₂
badge Registry Numbers
EC Number 233-892-7
MDL Number MFCD00008270
thermostat Physical Properties
Melting Point 24 °C
Boiling Point 71-73 °C/35 mmHg(lit.)
inventory_2 Storage & Handling
Density 0.832 g/mL at 20 °C(lit.)
Storage 2~8°C

description Product Description

Used extensively in organic synthesis as a silylating agent, it effectively protects hydroxyl, amino, and carboxyl groups during chemical reactions. It is particularly valuable in the preparation of sensitive intermediates where selective protection is required. In pharmaceuticals, it aids in the synthesis of complex drug molecules by ensuring stability and reactivity of functional groups. Additionally, it is employed in the derivatization of compounds for gas chromatography and mass spectrometry, enhancing volatility and detectability of analytes. Its role in peptide synthesis is also notable, where it facilitates the modification of amino acids to improve reaction efficiency.

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Test Parameter Specification
Purity 95-100
Refractive Index (20°C) 1.416-1.419
Specific Gravity (20°C) 0.831-0.833
Appearance Colorless to light yellow liquid
Infrared Spectrum Conforms to Structure
Note Low melting point solid; may change state in different environments (solid, liquid, or semi-solid)

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 2.5L
10-20 days ฿13,680.00
inventory 5ml
10-20 days ฿300.00
inventory 25ml
10-20 days ฿410.00
inventory 100ml
10-20 days ฿870.00
inventory 500ml
10-20 days ฿2,880.00

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N,O-Bis(trimethylsilyl)acetamide (TMS-BA)
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Used extensively in organic synthesis as a silylating agent, it effectively protects hydroxyl, amino, and carboxyl groups during chemical reactions. It is particularly valuable in the preparation of sensitive intermediates where selective protection is required. In pharmaceuticals, it aids in the synthesis of complex drug molecules by ensuring stability and reactivity of functional groups. Additionally, it is employed in the derivatization of compounds for gas chromatography and mass spectrometry, enhanc

Used extensively in organic synthesis as a silylating agent, it effectively protects hydroxyl, amino, and carboxyl groups during chemical reactions. It is particularly valuable in the preparation of sensitive intermediates where selective protection is required. In pharmaceuticals, it aids in the synthesis of complex drug molecules by ensuring stability and reactivity of functional groups. Additionally, it is employed in the derivatization of compounds for gas chromatography and mass spectrometry, enhancing volatility and detectability of analytes. Its role in peptide synthesis is also notable, where it facilitates the modification of amino acids to improve reaction efficiency.

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