N,O-Bis(trimethylsilyl)acetamide (TMS-BA)
95%
science Other reagents with same CAS 10416-59-8
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description Product Description
Used extensively in organic synthesis as a silylating agent, it effectively protects hydroxyl, amino, and carboxyl groups during chemical reactions. It is particularly valuable in the preparation of sensitive intermediates where selective protection is required. In pharmaceuticals, it aids in the synthesis of complex drug molecules by ensuring stability and reactivity of functional groups. Additionally, it is employed in the derivatization of compounds for gas chromatography and mass spectrometry, enhancing volatility and detectability of analytes. Its role in peptide synthesis is also notable, where it facilitates the modification of amino acids to improve reaction efficiency.
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| Test Parameter | Specification |
|---|---|
| Purity | 95-100 |
| Refractive Index (20°C) | 1.416-1.419 |
| Specific Gravity (20°C) | 0.831-0.833 |
| Appearance | Colorless to light yellow liquid |
| Infrared Spectrum | Conforms to Structure |
| Note | Low melting point solid; may change state in different environments (solid, liquid, or semi-solid) |
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