Used primarily as a reagent in organic synthesis for the introduction of the triethylsilyl group, which serves as a protective group for alcohols and other sensitive functional groups. It is particularly valuable in the synthesis of complex organic molecules, including pharmaceuticals and natural products, where selective protection and deprotection of hydroxyl groups are required. Additionally, it finds application in the modification of surfaces and materials, where its reactivity with hydroxyl groups on surfaces like glass or silica is exploited to impart hydrophobic properties. This makes it useful in the production of water-repellent coatings and in the preparation of chromatographic stationary phases.