Ethoxyamine hydrochloride is widely used in organic synthesis as a versatile reagent. It is particularly valuable in the preparation of oxime derivatives, which are essential intermediates in the synthesis of various pharmaceuticals and agrochemicals. The compound is also employed in the protection of carbonyl groups during complex chemical reactions, ensuring selective transformations. Additionally, it plays a role in the modification of nucleosides and nucleotides, aiding in the development of antiviral and anticancer drugs. Its application extends to the field of analytical chemistry, where it is used for the derivatization of aldehydes and ketones to enhance their detection in chromatographic analyses.