Used primarily as a chiral derivatizing agent in the resolution of racemic mixtures, especially for determining enantiomeric purity of chiral alcohols and amines. Its high reactivity allows it to form diastereomeric esters or amides with enantiomers, which can then be separated using standard chromatographic techniques. Due to the presence of the trifluoromethyl and methoxy groups, the resulting derivatives are often easily analyzable by NMR or HPLC, enabling accurate determination of enantiomeric excess. It is particularly valuable in asymmetric synthesis and pharmaceutical analysis where stereochemistry significantly impacts biological activity.