Used as an antidote in organophosphate poisoning, such as from insecticides or nerve agents. It works by reactivating acetylcholinesterase, an enzyme critical for normal nerve function that becomes inhibited by organophosphates. Most effective when administered early, especially before aging of the enzyme-inhibitor complex occurs. Often used alongside atropine to manage symptoms like excessive salivation, muscle twitching, and respiratory distress. Commonly used in emergency and military settings where exposure to toxic organophosphates is a risk.