Used primarily as a silyl protecting agent in organic synthesis, especially for alcohols and phenols. It selectively shields hydroxyl groups during multi-step reactions, improving stability and controlling reactivity. Commonly employed in the synthesis of complex molecules like pharmaceuticals and natural products. Its bulky structure offers steric protection, enhancing selectivity in reactions. Also used in modifying silica surfaces for chromatography and in the preparation of silylated derivatives for analytical techniques such as GC or MS.