Isobutyl chloroformate is widely used in organic synthesis, particularly in peptide coupling reactions. It acts as a reagent to facilitate the formation of amide bonds between amino acids, making it essential in the production of peptides and proteins. Additionally, it is employed in the preparation of carbamates and carbonates, which are important intermediates in pharmaceutical and agrochemical manufacturing. Its role in esterification reactions also makes it valuable in the synthesis of various esters used in flavors, fragrances, and polymers. Due to its reactivity, it is often handled under controlled conditions to ensure safety and efficiency in laboratory and industrial applications.