Used as a highly effective organocatalyst in asymmetric synthesis, particularly in promoting enantioselective transformations such as aldol reactions and Michael additions. Its strong hydrogen-bonding capability due to the urea moiety and electron-withdrawing trifluoromethyl groups enhances substrate activation and stereocontrol. Also employed in anion binding applications and supramolecular chemistry because of its ability to form stable complexes with anions through hydrogen bonding. Additionally, it serves as a building block in the design of functional materials requiring precise molecular recognition.