Used as a chiral base in asymmetric synthesis, particularly in deprotonation reactions where stereochemical control is critical. Commonly employed in lithiation reactions to generate chiral organolithium reagents. Also serves as a ligand in transition metal catalysis, enhancing enantioselectivity in various organic transformations. Applied in the resolution of racemic mixtures, especially in pharmaceutical synthesis where enantiopurity is essential. Its utility extends to research settings for studying reaction mechanisms involving chiral intermediates.