Diisopinocampheylborane (Ipc₂BH) is a chiral dialkylborane reagent widely used in asymmetric synthesis, particularly for enantioselective hydroboration of alkenes. It enables highly stereoselective addition of boron and hydrogen across carbon-carbon double bonds, followed by oxidation to produce chiral alcohols with excellent optical purity. It is especially effective for the hydroboration of cis-disubstituted and terminal alkenes, converting them into valuable chiral building blocks. The reagent's bulky structure provides superior stereochemical control, making it essential in the synthesis of complex natural products, pharmaceuticals, and other bioactive molecules where precise stereochemistry is required. Its high selectivity simplifies synthetic routes by minimizing the need for additional stereocontrol measures.