Lithium triisopropoxy(4-(trifluoromethyl)pyridin-2-yl)borate is an organoborate reagent used in advanced organic synthesis, particularly as a nucleophilic boron source in cross-coupling reactions such as the Suzuki-Miyaura coupling. It facilitates the introduction of the 4-(trifluoromethyl)pyridin-2-yl moiety into aryl and heteroaryl frameworks, forming carbon-carbon bonds essential for constructing complex molecules. Compared to other borates, it exhibits enhanced stability to air and moisture, simplifying laboratory handling. This reagent enables efficient reactions under mild conditions, improving yields and reducing byproducts. It is particularly valuable in the production of pharmaceuticals, agrochemicals, and specialty materials requiring heterocyclic components.