(R)-()-α,α-Diphenylprolinol
99%
Reagent
Code: #65704
Alias
α,α-Diphenyl-D-prolinol (R)-2-(diphenylhydroxymethyl)pyrrolidine +)-α,α-Diphenylprolinol (R)-(+)-α-Diphenyl-2-pyrrolidinemethanol
CAS Number
22348-32-9
blur_circular Chemical Specifications
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Molecular Information
Weight
253.34 g/mol
Formula
C₁₇H₁₉NO
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Registry Numbers
MDL Number
MFCD00077754
thermostat
Physical Properties
Melting Point
77-80 °C
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Storage & Handling
Storage
room temperature
description Product Description
Used as a chiral auxiliary in asymmetric synthesis, particularly in the formation of enantiomerically pure compounds. It is widely employed in organic chemistry to induce chirality in reactions such as aldol condensations, Michael additions, and Diels-Alder reactions. Its sterically demanding structure helps control the stereochemistry of the products, making it valuable in the synthesis of pharmaceuticals and fine chemicals. Additionally, it serves as a precursor for chiral catalysts and ligands in transition metal-catalyzed processes, enhancing selectivity and efficiency in complex molecular transformations.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Melting point | 77-80 |
| Purity (Titration by HClO4) | 98.5-101.5% |
| Purity | 99-100% |
| Chloroform | 65-69 |
| Appearance | White to off-white powder or crystals |
| Infrared Spectrum | Conforms to Structure |
| Solubility in Chloroform | Almost transparent |
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