(S)-(-)-7-[4(S)-(Benzyl)oxazol-2-yl]-7-di(3,5-di-t-butylphenyl)phosphino-2,2,3,3-tetrahydro-1,1-spirobiindane
98%
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This chemical is primarily utilized as a chiral ligand in asymmetric catalysis, particularly in transition metal-catalyzed reactions. Its unique structure, featuring a spirobiindane backbone and phosphine groups, makes it highly effective in inducing enantioselectivity. It is commonly employed in hydrogenation reactions, where it helps produce chiral molecules with high optical purity. Additionally, it finds application in cross-coupling reactions, such as Suzuki-Miyaura and Heck reactions, enabling the synthesis of complex organic compounds with precise stereochemistry. Its sterically demanding and electronically tunable properties make it a valuable tool in pharmaceutical and fine chemical industries for the synthesis of enantiomerically pure intermediates and active pharmaceutical ingredients (APIs).
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