N-(4-Trifluoromethylbenzyl)cinchoninium Bromide
98%
Reagent
Code: #70668
CAS Number
95088-20-3
blur_circular Chemical Specifications
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Molecular Information
Weight
533.42 g/mol
Formula
C₂₇H₂₈BrF₃N₂O
thermostat
Physical Properties
Melting Point
245 °C (dec.)(lit.)
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Storage & Handling
Storage
Room temperature, sealed, dry
description Product Description
Used as a chiral phase-transfer catalyst in asymmetric synthesis, particularly in the enantioselective alkylation of glycine derivatives to produce optically active amino acids. It facilitates the formation of chiral centers with high enantiomeric excess, making it valuable in the synthesis of pharmaceuticals and fine chemicals. Additionally, it is employed in the preparation of intermediates for drugs and agrochemicals, where precise stereochemistry is critical for biological activity. Its trifluoromethyl group enhances its catalytic efficiency and stability under various reaction conditions.
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