(S)-3-Iodotetrahydrofuran is primarily used as a chiral building block in organic synthesis, particularly in the production of pharmaceuticals and fine chemicals. Its iodine atom makes it a versatile intermediate for coupling reactions, such as Suzuki-Miyaura or Sonogashira reactions, enabling the construction of complex molecular structures. The chiral center in the molecule allows for the synthesis of enantiomerically pure compounds, which is crucial in drug development to ensure specific biological activity. Additionally, it is employed in the preparation of heterocyclic compounds, which are often key components in medicinal chemistry. Its application extends to material science, where it aids in the development of chiral materials with potential use in asymmetric catalysis or optoelectronic devices.