(4-Chloro-3-(4-ethoxybenzyl)phenyl)((3aS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)methanone

97%

Reagent Code: #36899
fingerprint
CAS Number 1103738-30-2

science Other reagents with same CAS 1103738-30-2

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 432.89 g/mol
Formula C₂₃H₂₅ClO₆
badge Registry Numbers
MDL Number MFCD25977360
thermostat Physical Properties
Boiling Point 601.7°C at 760 mmHg
inventory_2 Storage & Handling
Storage Room temperature, dry and sealed

description Product Description

This compound serves as a critical intermediate in medicinal chemistry, particularly in the synthesis of antiviral pharmaceuticals such as Remdesivir (GS-5734). Its structure consists of a 4-chloro-3-(4-ethoxybenzyl)phenyl methanone attached to a stereospecifically protected furanose moiety ((3aS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl), mimicking a ribose derivative. This enables the construction of nucleoside analogs targeting viral RNA-dependent RNA polymerases, effective against coronaviruses and other RNA viruses. The defined stereochemistry and functional groups facilitate selective modifications, optimizing drug potency, selectivity, and pharmacokinetics. It is widely used in industrial-scale production and academic research for structure-activity relationship (SAR) studies in antiviral drug discovery.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿3,888.00
inventory 1g
10-20 days ฿9,747.00
inventory 5g
10-20 days ฿29,358.00
inventory 10g
10-20 days ฿48,879.00

Cart

No products

Subtotal: 0.00
Total 0.00 THB
(4-Chloro-3-(4-ethoxybenzyl)phenyl)((3aS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)methanone
No image available

This compound serves as a critical intermediate in medicinal chemistry, particularly in the synthesis of antiviral pharmaceuticals such as Remdesivir (GS-5734). Its structure consists of a 4-chloro-3-(4-ethoxybenzyl)phenyl methanone attached to a stereospecifically protected furanose moiety ((3aS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl), mimicking a ribose derivative. This enables the construction of nucleoside analogs targeting viral RNA-dependent RNA polymerases, effectiv

This compound serves as a critical intermediate in medicinal chemistry, particularly in the synthesis of antiviral pharmaceuticals such as Remdesivir (GS-5734). Its structure consists of a 4-chloro-3-(4-ethoxybenzyl)phenyl methanone attached to a stereospecifically protected furanose moiety ((3aS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl), mimicking a ribose derivative. This enables the construction of nucleoside analogs targeting viral RNA-dependent RNA polymerases, effective against coronaviruses and other RNA viruses. The defined stereochemistry and functional groups facilitate selective modifications, optimizing drug potency, selectivity, and pharmacokinetics. It is widely used in industrial-scale production and academic research for structure-activity relationship (SAR) studies in antiviral drug discovery.

Mechanism -
Appearance -
Longevity -
Strength -
Storage -
Shelf Life -
Allergen(s) -
Dosage (Range) -
Dosage (Per Day) -
Mix Method -
Heat Resistance -
Stable in pH range -
Solubility -
Product Types -
INCI -

Purchase History for

Loading purchase history...