(S)-2-(bis(3,5-dimethylphenyl)((trimethylsilyl)oxy)methyl)pyrrolidine
97%
Reagent
Code: #237687
CAS Number
848821-60-3
blur_circular Chemical Specifications
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Molecular Information
Weight
381.63 g/mol
Formula
C₂₄H₃₅NOSi
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Registry Numbers
MDL Number
MFCD14636497
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Storage & Handling
Storage
2-8°C, light-proof, inert gas
description Product Description
Used as a chiral auxiliary in asymmetric synthesis, particularly in enantioselective organocatalysis. It helps control stereochemistry in carbon-carbon bond-forming reactions, such as aldol or Mannich-type reactions, by directing the approach of reagents through steric and electronic effects. The silyloxy group enhances stability and modulates reactivity, while the pyrrolidine core acts as an organocatalyst scaffold. Commonly employed in the synthesis of complex natural products and pharmaceuticals where high enantiomeric excess is required. Its bulky aryl groups provide excellent stereoselectivity, making it valuable in advanced intermediate synthesis.
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