Used in organic synthesis primarily as an organocatalyst for enantioselective reactions, such as asymmetric Diels-Alder and other transformations involving iminium or enamine intermediates. Its rigid imidazolidinone core, derived from proline, enables high levels of stereocontrol, making it essential in the preparation of pharmaceuticals and biologically active compounds with specific stereochemistry. The dichloroacetic acid salt form enhances solubility and reactivity under acidic conditions. Widely applied in catalysis and medicinal chemistry research where precise molecular spatial arrangement is critical.