((R)-1-Phenyl-ethyl)-(3-trimethylsilanyl-prop-2-ynyl)-amine
Reagent
Code: #229546
CAS Number
2219358-58-2
blur_circular Chemical Specifications
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Molecular Information
Weight
231.413 g/mol
Formula
C₁₄H₂₁NSi
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Storage & Handling
Storage
2-8°C
description Product Description
Used as a chiral amine catalyst in asymmetric synthesis, particularly in enantioselective alkylation and amination reactions. Its bulky trimethylsilyl group enhances stereoselectivity by influencing the transition state geometry. Commonly employed in pharmaceutical intermediates synthesis where high enantiomeric excess is required. Also serves as a building block in the preparation of functionalized propargylamines, which are key motifs in bioactive molecules and organic materials.
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