(R)-N-((S)-1-(2-((tert-Butyldiphenylsilyl)oxy)phenyl)-2-(diphenylphosphino)ethyl)-2-methylpropane-2-sulfinamide
95%
Reagent
Code: #53881
CAS Number
1803239-59-9
science Other reagents with same CAS 1803239-59-9
blur_circular Chemical Specifications
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Molecular Information
Weight
663.9200 g/mol
Formula
C₄₀H₄₆NO₂PSSi
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Registry Numbers
MDL Number
MFCD32697178
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Storage & Handling
Storage
2-8°C
description Product Description
This compound is primarily utilized in asymmetric synthesis as a chiral ligand or catalyst, enabling the formation of enantiomerically pure products in organic reactions. Its unique structure, featuring both sulfinamide and phosphine groups, makes it particularly effective in transition metal-catalyzed processes, such as asymmetric hydrogenation or carbon-carbon bond-forming reactions. The tert-butyldiphenylsilyl group provides steric protection, enhancing selectivity during catalysis. It is often employed in the pharmaceutical industry for the synthesis of chiral intermediates in drug development, ensuring high enantioselectivity and yield. Additionally, its application extends to the preparation of complex natural products and fine chemicals, where precise stereocontrol is critical.
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