(4S,5R)-4,5-Diphenyl-2-(5-(trifluoromethyl)pyridin-2-yl)-4,5-dihydrooxazole
97%,99%ee
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This chiral dihydrooxazole is primarily utilized as a ligand in asymmetric catalysis for organic synthesis and pharmaceutical research, owing to its complex structure featuring (4S,5R)-4,5-diphenyl substituents for steric control and a 5-(trifluoromethyl)pyridin-2-yl group for electronic tuning. It enables highly enantioselective reactions, such as conjugate additions and allylic alkylations, facilitating the production of enantiomerically pure compounds essential for chiral drug candidates with improved binding affinity and metabolic stability. Its applications also extend to materials science, where it supports the creation of advanced organic materials with unique electronic or optical properties.
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