(S)-2-(2-(Diphenylphosphino)benzyl)-4-phenyl-4,5-dihydrooxazole
97%
Reagent
Code: #237971
CAS Number
761402-27-1
blur_circular Chemical Specifications
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Molecular Information
Weight
421.47 g/mol
Formula
C₂₈H₂₄NOP
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Storage & Handling
Storage
2-8°C, Sealed, Dry, Light-proof, Inert Gas
description Product Description
Used as a chiral ligand in asymmetric catalysis, particularly in transition metal-catalyzed reactions such as rhodium- or ruthenium-mediated enantioselective hydrogenation of prochiral olefins and ketones. Its phosphine-oxazoline structure provides excellent stereocontrol, making it valuable in the synthesis of optically active pharmaceuticals and fine chemicals. Commonly employed in asymmetric C–C bond-forming reactions and cycloadditions where high enantioselectivity is required. Also utilized in palladium-catalyzed allylic substitutions to produce chiral intermediates with high ee values.
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