Used as a chiral ligand in asymmetric catalysis, particularly in enantioselective organic transformations. Its rigid biimidazole framework with defined stereochemistry makes it effective in coordinating transition metals like copper or nickel, enabling high enantioselectivity in reactions such as conjugate additions and cyclopropanations. The ethyl and p-tolyl substituents enhance solubility and influence steric and electronic properties, improving catalyst performance. Commonly applied in pharmaceutical synthesis where precise stereocontrol is critical.