Widely used as a chiral ligand in asymmetric catalysis, this compound plays a key role in enantioselective transformations, particularly in rhodium- and ruthenium-catalyzed asymmetric hydrogenation reactions. It is highly effective in the synthesis of chiral amines, alcohols, and other stereochemically complex molecules important in pharmaceutical manufacturing. Due to its well-defined chiral environment and strong coordination to transition metals, it enables high enantioselectivity and catalytic efficiency. Its application is especially valuable in the development of active pharmaceutical ingredients (APIs) where control of stereochemistry is critical for biological activity and regulatory approval.