(1S)-3,3′-Difluoro[1,1′-binaphthalene]-2,2′-diol
98%
science Other reagents with same CAS 1399050-57-7
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Used as a chiral ligand in asymmetric catalysis, particularly in enantioselective synthesis of pharmaceuticals and fine chemicals. Its rigid binaphthyl backbone and hydroxyl groups enable strong coordination with metal centers, enhancing stereocontrol in reactions such as asymmetric allylic alkylation and transfer hydrogenation. The difluoro substitution improves electronic properties and binding selectivity, leading to higher enantiomeric excess in products. Commonly employed in ruthenium- or titanium-based catalytic systems for producing single-enantiomer compounds.
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