Used as a highly effective chiral ligand in asymmetric catalysis, particularly in enantioselective transformations such as hydrogenation and C–C bond-forming reactions. Its sterically bulky structure enhances selectivity by creating a well-defined chiral environment around the metal center, leading to high enantiomeric excess in the products. Commonly employed with rhodium, ruthenium, or iridium complexes, it is valued in pharmaceutical synthesis where precise stereochemistry is critical. Its air-stable phosphine oxide form allows for easier handling and storage compared to traditional phosphines.