Used as a chiral ligand in asymmetric catalysis, particularly in enantioselective organic transformations. Its rigid cyclobutane core and oxazoline rings provide a well-defined chiral environment, making it effective in copper-catalyzed cyclopropanation, Diels-Alder, and aldol reactions. Commonly employed in the synthesis of optically active compounds for pharmaceuticals and fine chemicals. Shows high enantioselectivity with various substrates due to its steric and electronic tuning. Also utilized in coordination chemistry with transition metals to form catalysts for stereoselective synthesis.