(2S,2'S)-1,1'-Bis[(S)-(dimethylamino)phenylmethyl]-2,2'-bis(diphenylphosphino)ferrocene
98%
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Widely used as a chiral ligand in asymmetric catalysis, this compound plays a key role in enantioselective transformations, particularly in rhodium- and palladium-catalyzed reactions. It is highly effective in asymmetric hydrogenation of prochiral olefins and imines, enabling the synthesis of chiral amines, amino acids, and other pharmaceutical intermediates with high enantiomeric excess. Its rigid ferrocene backbone and well-defined chiral environment enhance stereocontrol, making it valuable in the development of active pharmaceutical ingredients (APIs) where stereochemistry is critical. The ligand is also employed in C–C bond-forming reactions, such as asymmetric allylic alkylation, contributing to the efficient construction of complex chiral molecules in fine chemical synthesis.
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