(4S,4'S)-4,4'-Di-sec-butyl-4,4',5,5'-tetrahydro-2,2'-bioxazole
98%
science Other reagents with same CAS 2374958-89-9
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Used as a chiral ligand in asymmetric catalysis, particularly in enantioselective organic transformations. Its rigid oxazoline framework enhances stereocontrol, making it effective in reactions such as asymmetric allylic alkylation, Diels-Alder cycloadditions, and copper-catalyzed conjugate additions. The sec-butyl groups contribute to high enantioselectivity by creating a well-defined chiral environment around the metal center. Commonly employed with transition metals like copper, palladium, or nickel to achieve high yields and excellent ee values in the synthesis of chiral building blocks for pharmaceuticals and fine chemicals.
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