Used as a chiral ligand in asymmetric catalysis, particularly in enantioselective organic transformations. Its rigid biimidazole backbone and stereogenic centers make it effective in coordinating transition metals like copper or nickel, enabling high enantioselectivity in reactions such as conjugate additions and cyclopropanations. The isopropyl and m-tolyl groups enhance steric and electronic tuning, improving selectivity and catalyst stability. Commonly applied in pharmaceutical synthesis where precise stereochemistry is critical.